3. Lab Scale development
Once a customer’s application and concept are understood, a material development project typically begins with series of lab-scale trials using Bioinicia’s single-emitter Fluidnatek® apparatus, to select the most appropriate formulation for electrospinning or electrospraying. This step involves: 1.Selection of material (e.g. polymer, protein etc) to provide the required product performance 2. Selection of solvent system to enable the processing of the selected material by electrospinning / electrospraying. 3.Optimisation of the solution properties (viscosity, surface tension, conductivity, volatility etc.) to achieve stable processing conditions<br />
In parallel with formulation optimisation, the key processing parameters (solution flow rate, applied voltages, processing distance, temperature & humidity) are also optimised in order to generate the required nano and micro-structured morphologies. 4. Samples of the materials are produced and characterized for comparison with the validation criteria. This iterative process continues until the required material properties are obtained. All of the information obtained is then used in transferring the process to Bioinicia’s pilot-scale multi-emitter electrospinning / electrospraying equipment for scale-up of fiber or particle production.