EHDP, also commonly referred to as electrospinning process (for fibers) or electrospraying (for particles), is the voltage-driven fabrication technology at the core of Bioinicia’s Fluidnatek ® equipment range. Both electrospinning process and electrospraying process have been investigated thoroughly in academia over the last 25 years as a means to fabricate nano and/or micro-structured fibers and particles and are now being adopted by industry for a broad range of applications. The electrospinning process as well as electrospraying are becoming an advantageous option in some industrial applications replacing other traditional techniques used so far such as the spray-drying or the lyophilization because of the special benefits and distinguishing characteristics that electrospinning and electrospraying provide. Look to the frame on the right to find out more about the particular characteristics of electrospinning process.
There are several key characteristics which differentiate this technology based on electrospinning process and electrospraying from alternative processes:
– Produces dry product in a single step: powder (electrospraying process) or non-woven fiber membranes, coatings and complex shapes (electrospinning process).
– Room temperature operation suitable for processing labile components e.g. antioxidants, living cells, pharmaceutical ingredients, omega-3 oils, etc…
– Electrospinning process is suitable for an extensive portfolio of materials, including polymers, proteins, inorganic materials and composites, providing the flexibility to tailor the products’ properties according to the application requirements
– Capable of producing single-phase or multi-component fibers and particles e.g. blended or core-shell structures (being the coaxial electrospinning process one of the most well- known processes of interest for researchers)
Coaxial electrospinning is doable with a single-nozzle injector but also using a multi-nozzle spinning head, in order to produce larger batches
– Enables high efficiency encapsulation of bioactive ingredients or functional compounds
The electrospinning process (as well as the electrospraying process) gets to dry and encapsulate in just one single step
– Tightly controlled fiber and particle dimensions (50nm to 10um range)
– Continuous production process allowing for industrial scalability is another significant benefit of electrospinning process
– Low energy-consumption compared with other drying processes
– Can be used within cleanroom facilities and validated for GMP or ISO13485 processing