Myocardial infarction causes about 2 million deaths in Europe each year. The REBORN project is focused on developing an advanced cardiac patch to regenerate heart tissue following a myocardial infarction, preventing adverse heart remodeling and scar tissue formation. Our ultimate goal is to create an acellular, piezoelectric patch capable of releasing anti-inflammatory, anti-fibrotic, and cardiomyocyte-proliferative factors on demand. In addition, we are developing an ultrasound stimulation system and a novel in vitro cardiac model for validation.
Electrospinning is a groundbreaking technique in the biomedical field, offering the long-sought promise of holistic tissue restoration. At BIOINICIA, we are dedicated to advancing scientific knowledge and pushing the boundaries of what electrospinning can achieve. Our commitment to disruptive innovation drives us to explore new frontiers in the sector.
With a vision of producing a minimally invasive patch, our multidisciplinary consortium leverages advanced materials and state-of-the-art electrospun fibers to restore cardiac function. In this insightful video, you can learn more about our project and its potential to transform thousands of lives around the world:
This initiative brings together experts from various fields, highlighting the importance of collaboration and innovation. Partnering with five universities, and eight private companies, representing five different nationalities, we are proud to be a part of the REBORN project, funded by the European Commission. The project’s multidisciplinary approach integrates expertise in bioengineering, materials science, and clinical applications to create a comprehensive solution for cardiac regeneration. BIOINICIA contributes its extensive experience in developing micro and nanofiber-based membranes using electrospinning at a pre-industrial scale, backed by GMP and ISO13485 certifications for patch manufacturing.
The REBORN project marks a significant advancement in medical technology, offering new hope for patients with heart conditions. It showcases the potential of electrospun materials in biomedical applications and underscores the societal benefits of investing in cutting-edge scientific projects.
For more details, please visit the oficial webpage.
Project details
- PROJECT NUMBER: 101091852
- PROJECT TITLE: Remodelling of the infarcted heart: piezoelectric multifunctional patch enabling the sequential release of therapeutic factors
- TOPIC: HORIZON-CL4-2022-RESILIENCE-01-13
- START DATE: 01 January 2023
- DURATION: 48 Months
- GRANTING AUTHORITY: European Health and Digital Executive Agency
- EU CONTRIBUTION: € 4.050.412,50 Euro
“Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do notnecessarily reflect those of the European Union or the European Health and Digital Executive Agency (HADEA). Neither the European Union nor the granting authority can be held responsible for them.”